About Fabio Cumbo

I’m a Software Engineer and Researcher with a Ph.D. in Computer Science and Automation Engineering, currently a Research Associate at the Blankenberg Lab, Computational Life Sciences, Cleveland Clinic Research, Cleveland, Ohio, USA.

My work sits at the intersection of bioinformatics, machine learning, and hyperdimensional computing — building computational tools and methods to tackle open challenges in microbial genomics and biomedical data analysis.

My scientific portfolio — peer-reviewed journal articles, conference proceedings, and pre-print manuscripts — is available on my Google Scholar profile. My curriculum vitae can be downloaded here.

Always open to new collaborations — feel free to reach out at fabio.cumbo@gmail.com or cumbof@ccf.org.

Research Interests

My research interests include but are not limited to:

  • Bioinformatics: developing computational methods in metagenomics for the discovery and characterization of known and yet-to-be-named microbial species, with a focus on strain-level taxonomy and large-scale metagenomic profiling;

  • Machine Learning: designing energy- and memory-efficient machine learning methods for analyzing large-scale biomedical datasets;

  • Hyperdimensional Computing: developing and applying Hyperdimensional Computing (Vector-Symbolic Architectures) to artificial intelligence and bioinformatics problems, including classification and feature selection on high-dimensional metagenomic data;

  • Quantum Computing: exploring the intersection of quantum computing and Hyperdimensional Computing, and the development of new quantum neuromorphic architectures.

Highlights

DateEvent
03/2026📝 Appointed Associate Editor for Frontiers in Bioinformatics – Genomic Analysis
02/2026🌱 Started a new position as Research Associate at Computational Life Sciences, Cleveland Clinic Research, Cleveland, OH, USA
12/2025📝 Appointed Associate Editor for Frontiers in Cellular and Infection Microbiology – Extra-intestinal Microbiome
06/2025🗣️ Presented “Towards the automatic integration of tools in Galaxy: the anvi’o suite and a new AI-driven automation pipeline” with a talk at the Galaxy Bioconductor Community Conference (GBCC2025) in Cold Spring Harbor, NY, USA
05/2025🏆 Awarded with the Galaxy Bioconductor Community Conference (GBCC2025) Travel Fellowship
02/2025🗣️ Invited speaker at the MeDOC Consortium with a talk titled “MetaSBT: a scalable framework for the characterization of still unknown microbes in metagenomic samples
01/2025🗣️ Invited speaker at the MetaSUB International Consortium with a talk titled “Investigating the hidden diversity of viruses in metagenomic samples with MetaSBT
11/2024🗣️ Presented “Investigating the hidden diversity of viruses in metagenomic samples with MetaSBT” as a selected long talk at the Biological Data Science Meeting at Cold Spring Harbor Laboratories in Cold Spring Harbor, NY, USA
08/2024🎓 Certificate of Quantum Excellence issued by IBM for successfully completing the Qiskit Global Summer School 2024
07/2024🗣️ Presented “Building Vector-Symbolic Architectures with Python” with a talk at PyOhio in Cleveland, OH, USA
03/2024🏆 Cleveland Clinic Excellence Award in recognition of demonstrated exceptional outstanding achievements
11/2023🗣️ Invited speaker at the Institute for Systems Analysis and Computer Science “Antonio Ruberti” in Rome, Italy, with two talks titled “Towards revealing the hidden diversity of the microbial dark matter and its relation to host health and environmental factors” and “Computing with high-dimensional vectors: theory and applications in bioinformatics
07/2023🗣️ Presented “Investigating the known and unknown microbial composition of metagenomic samples made easy with MetaSBT in Galaxy” with a poster and talk at the Galaxy Community Conference (GCC2023) in Brisbane, Queensland, Australia
09/2022🗣️ Presented “Feature selection with vector-symbolic architecture: a case study on microbial profiles of shotgun metagenomic samples of colorectal cancer” with a poster at the 9th Annual Genetics Education Symposium organized by the Cleveland Clinic Genomic Medicine Institute and the Center for Personalized Genetic Healthcare in Cleveland, OH, USA
08/2022🎓 Certificate of Quantum Excellence issued by IBM for successfully completing the Qiskit Global Summer School 2022
07/2022🗣️ Presented “Microbial Strain Characterization and Subtyping of Metagenome-Assembled Genomes With Sequence Bloom Trees in Galaxy” with a poster and talk at the Galaxy Community Conference (GCC2022) in Minneapolis, MN, USA
05/2022🏆 Awarded with the Galaxy Community Conference (GCC2022) Fellowship
03/2022🌱 Started a new position as Postdoctoral Fellow at the Blankenberg Lab, Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, OH, USA